Assessment of the Micronucleus Assay and Analysis of Fish RBCs Exposed to Pyridaben in Hypophthalmichthys Molitrix and Labeo Rohita: A Public Health Concern

Authors

  • Shahid Rauf Institute of Zoological Science, University of Peshawar, Pakistan.
  • Muhammad Zohaib Ullah Khan Institute of Zoological Sciences, University of Peshawar, Pakistan.
  • Abdur Rahman Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan.
  • Khalid Rehman Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan.
  • , Israr Khan Institute of Zoological Science, University of Peshawar, Pakistan.
  • Ayesha Shams Institute of Zoological Science, University of Peshawar, Pakistan.

DOI:

https://doi.org/10.59644/oaphhar.1(1).233

Keywords:

Pyridaben, Micronuclei, Chemicals, Labeo Rohita, Hypophthalmichthys Molitrix

Abstract

The present study was conducted to examine how exposure to pyributicarb affects the shape of red blood cells (RBCs) and the production of micronuclei in two commercially significant fish species: Labeo rohita (Rohu) and Hypophthalmichthys molitrix (silver carp). Pyribaden is a chemical that is commonly used in agriculture and has been linked to several harmful impacts on aquatic life. In the present study, 33 specimens were taken and exposed to Pyribaden. Blood then blood sample were taken and a micro assay on them. The results show that micronuclei were formed, and production was increased by increasing the chemical concentration. These results point to the possibility of genotoxic and hematotoxic effects of pyridabin on fish, underscoring the need for more investigation to clarify its modes of action and any possible ecological ramifications. To evaluate pyridabin overall toxicity and implement practical mitigation techniques to protect aquatic ecosystems, it is imperative to understand the effects of pyrabaden on fish red blood cells. We need to act regarding the control of pesticides, such as pyridabin and others like it, to control aquatic pollution.

Published

2025-10-23

How to Cite

Shahid Rauf, Muhammad Zohaib Ullah Khan, Abdur Rahman, Khalid Rehman, , Israr Khan, & Ayesha Shams. (2025). Assessment of the Micronucleus Assay and Analysis of Fish RBCs Exposed to Pyridaben in Hypophthalmichthys Molitrix and Labeo Rohita: A Public Health Concern. Open Access Public Health and Health Administration Review, 1(1), 16–23. https://doi.org/10.59644/oaphhar.1(1).233