Collaborative Care in PCOS: Evaluating the Role of Radiologist and Gynecologist in Diagnosis and Management of PCOS
DOI:
https://doi.org/10.59644/oaphhar.4(2).283Keywords:
Hyperandrogenism, Longitudinal Weight Gain, Polycystic Ovary Syndrome, Pharmacoeconomics, Quality of LifeAbstract
One of the most prevalent hormonal disturbances is Polycystic ovary syndrome, which affects women's reproductive health. It disrupts the menstrual cycle, fertility, psychological health, and quality of life. This study aimed to evaluate the role of radiologists and gynecologists together in the diagnosis and management of polycystic ovarian syndrome. A cross-sectional observational study was conducted with a sample of 500 females who met the Rotterdam criteria. Three-quarters reported hirsutism (72.8%) and acne (73%), more than half were experiencing depression (60.6%), and half faced the deeply personal challenge of infertility (46%). Comorbidities added further weight — 15.4% were living with hypertension, and 10.2% with diabetes mellitus. Hyperandrogenism appeared as the strongest driver of inferior quality of life (p=0.01), closely followed by menstrual irregularity (p=0.044), while only 12.4% of women reported a regular menstrual cycle. Side effects from treatment were widespread — mood changes affected 74.2%, headaches 53.2%, abdominal pain 39.6%, and breast tenderness 35.4%. On the financial side, managing polycystic ovarian syndrome through combination therapy costs women an average of PKR 3,732 every month, a burden that stretched across a mean treatment duration of 2.4 years. Behind every polycystic ovarian syndrome diagnosis is a woman navigating a condition that touches every part of her life. The numbers in this study tell a clear story — this is not a condition that one specialist can manage alone. It calls for gynecologists and radiologists to work hand in hand, supported by treatment plans that are not only clinically sound but also affordable, compassionate, and genuinely built around the real lives of women in Pakistan.
References
March WA, Moore VM, Willson KJ, Phillips DI, Norman RJ, Davies MJ. The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria. Human reproduction. 2010;25(2):544-51. DOI: https://doi.org/10.1093/humrep/dep399
Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. The Journal of Clinical Endocrinology & Metabolism. 2004;89(6):2745-9. DOI: https://doi.org/10.1210/jc.2003-032046
Asunción M, Calvo RM, San Millán JL, Sancho J, Avila S, Escobar-Morreale HcF. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. The Journal of Clinical Endocrinology & Metabolism. 2000;85(7):2434-8. DOI: https://doi.org/10.1210/jc.85.7.2434
Diamanti-Kandarakis E, Kouli CR, Bergiele AT, Filandra FA, Tsianateli TC, Spina GG, et al. A survey of the polycystic ovary syndrome in the Greek island of Lesbos: hormonal and metabolic profile. The journal of clinical endocrinology & metabolism. 1999;84(11):4006-11. DOI: https://doi.org/10.1210/jcem.84.11.6148
Akram M, Roohi N. Endocrine correlates of polycystic ovary syndrome in Pakistani women. J Coll Physicians Surg Pak. 2015;25(1):22-6.
Teede HJ, Hutchison SK, Zoungas S. The management of insulin resistance in polycystic ovary syndrome. Trends in Endocrinology & Metabolism. 2007;18(7):273-9. DOI: https://doi.org/10.1016/j.tem.2007.08.001
Diamanti-Kandarakis E, Papavassiliou AG. Molecular mechanisms of insulin resistance in polycystic ovary syndrome. Trends in molecular medicine. 2006;12(7):324-32. DOI: https://doi.org/10.1016/j.molmed.2006.05.006
Teede H, Deeks A, Moran L. Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC medicine. 2010;8(1):41. DOI: https://doi.org/10.1186/1741-7015-8-41
Moran LJ, Pasquali R, Teede HJ, Hoeger KM, Norman RJ. Treatment of obesity in polycystic ovary syndrome: a position statement of the Androgen Excess and Polycystic Ovary Syndrome Society. Fertility and sterility. 2009;92(6):1966-82. DOI: https://doi.org/10.1016/j.fertnstert.2008.09.018
Hutchison SK, Stepto NK, Harrison CL, Moran LJ, Strauss BJ, Teede HJ. Effects of exercise on insulin resistance and body composition in overweight and obese women with and without polycystic ovary syndrome. The Journal of Clinical Endocrinology & Metabolism. 2011;96(1):E48-E56. DOI: https://doi.org/10.1210/jc.2010-0828
Harrison CL, Lombard CB, Moran LJ, Teede HJ. Exercise therapy in polycystic ovary syndrome: a systematic review. Human reproduction update. 2011;17(2):171-83. DOI: https://doi.org/10.1093/humupd/dmq045
Masroor D, Khaliq SA, Azhar I, Ahmad SM. Development and Validation of Questionnaire to compare treatment options of polycystic ovarian syndrome. J Int Res Med Pharm Sci. 2020;15(1):1-3.
Rodriguez-Paris D, Remlinger-Molenda A, Kurzawa R, Głowińska A, Spaczyński R, Rybakowski F, et al. Psychiatric disorders in women with polycystic ovary syndrome. Psychiatr Pol. 2019;53(4):955-66. DOI: https://doi.org/10.12740/PP/OnlineFirst/93105
Brewer M, Pawelczak M, Kessler M, Shah B. A review of polycystic ovarian syndrome in adolescents. Minerva pediatrica. 2010;62(5):459-73.
Greenwood E, Pasch L, Legro R, Cedars M, Huddleston H. Quality of life and depression in polycystic ovary syndrome. Fertility and sterility. 2017;108(3):e64-e5. DOI: https://doi.org/10.1016/j.fertnstert.2017.07.203
Sidra S, Tariq MH, Farrukh MJ, Mohsin M. Evaluation of clinical manifestations, health risks, and quality of life among women with polycystic ovary syndrome. PloS one. 2019;14(10):e0223329. DOI: https://doi.org/10.1371/journal.pone.0223329
Teede HJ, Joham AE, Paul E, Moran LJ, Loxton D, Jolley D, Lombard C. Longitudinal weight gain in women identified with polycystic ovary syndrome: results of an observational study in young women. Obesity. 2013;21(8):1526-32. DOI: https://doi.org/10.1002/oby.20213
Masroor D, Khaliq SA, Ahmad SM, Mazhar F, Azhar I. Pharmacoeconomic evaluation of treatments for Poly Cystic Ovarian Syndrome (PCOS). Cost Effectiveness and Resource Allocation. 2024;22(1):62. DOI: https://doi.org/10.1186/s12962-024-00569-6
Shih YCT, Halpern MT. Economic evaluations of medical care interventions for cancer patients: how, why, and what does it mean? CA: a cancer journal for clinicians. 2008;58(4):231-44. DOI: https://doi.org/10.3322/CA.2008.0008
Willett WC, Manson JE, Stampfer MJ, Colditz GA, Rosner B, Speizer FE, Hennekens CH. Weight, weight change, and coronary heart disease in women: risk within the'normal'weight range. Jama. 1995;273(6):461-5. DOI: https://doi.org/10.1001/jama.1995.03520300035033
Rachoń D, Teede H. Ovarian function and obesity—interrelationship, impact on women's reproductive lifespan and treatment options. Molecular and cellular endocrinology. 2010;316(2):172-9. DOI: https://doi.org/10.1016/j.mce.2009.09.026
Wright C, Zborowski J, Talbott E, McHugh-Pemu K, Youk A. Dietary intake, physical activity, and obesity in women with polycystic ovary syndrome. International journal of obesity. 2004;28(8):1026-32. DOI: https://doi.org/10.1038/sj.ijo.0802661
Moran LJ, Misso ML, Wild RA, Norman RJ. Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis. Human reproduction update. 2010;16(4):347-63. DOI: https://doi.org/10.1093/humupd/dmq001
Sitwat Zehra SZ, Afsheen Arif AA, Nargis Anjum NA, Abid Azhar AA, Masood Qureshi MQ. " Depression and anxiety in women with polycystic ovary syndrome from Pakistan". 2015.
Rasgon NL, Rao RC, Hwang S, Altshuler LL, Elman S, Zuckerbrow-Miller J, Korenman SG. Depression in women with polycystic ovary syndrome: clinical and biochemical correlates. Journal of affective disorders. 2003;74(3):299-304. DOI: https://doi.org/10.1016/S0165-0327(02)00117-9
Barnard L, Ferriday D, Guenther N, Strauss B, Balen A, Dye L. Quality of life and psychological well being in polycystic ovary syndrome. Human reproduction. 2007;22(8):2279-86. DOI: https://doi.org/10.1093/humrep/dem108
Kass B, Icke K, Witt CM, Reinhold T. Effectiveness and cost-effectiveness of treatment with additional enrollment to a homeopathic integrated care contract in Germany. BMC health services research. 2020;20(1):872. DOI: https://doi.org/10.1186/s12913-020-05706-4
Hughes GD, Aboyade OM, Okonji OC, Clark B, Bawa WA, Xavier C, Rasu RS. Cost of traditional herbal medicines for noncommunicable diseases in rural and urban communities in South Africa. Value in health regional issues. 2022;29:66-75. DOI: https://doi.org/10.1016/j.vhri.2021.08.006
Dewan D, Sharma RS, Nim PN, Singh SS. Homoeopathy a system of holistic Healing as an alternative treatment for PCOS–a review. International Journal of High Dilution Research-ISSN 1982-6206. 2021;20(4):43-59. DOI: https://doi.org/10.51910/ijhdr.v20i4.1126
Ernst E. Cost evaluation of herbal medicine. Journal of Herbal Pharmacotherapy. 2003;3(4):55-6. DOI: https://doi.org/10.1080/J157v03n04_04
De Beurs E, Warmerdam E, Oudejans S, Spits M, Dingemanse P, De Graaf S, et al. Treatment outcome, duration, and costs: a comparison of performance indicators using data from eight mental health care providers in the Netherlands. Administration and Policy in Mental Health and Mental Health Services Research. 2018;45(2):212-23. DOI: https://doi.org/10.1007/s10488-017-0818-x
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